COVID19 IFR will rise with Reinfection. SARS2 infects cyclically in populations as antibodies deplete?



As antibodies vanish, reinfection with SARS-CoV-2 creates a new comorbid underlying illness, COVID-19 itself, because of the cell damage each infection causes. This will raise the IFR and create an endless recycling pandemic until there are no more humans SARS2 is able to infect. Join the latter group by wearing an N95 mask.

The importance of some recent known SARS2 reinfection discoveries indicate an ominous danger that previous FPMag articles warned about.

“The virus is in the incipient stages of cycling through previously infected population. As it does so it will be worse because any person who has been infected previously may have hidden or even symptomatic chronic illness caused by cells damaged by SARS2,” explains Fred Harris, the biostatistician team lead of the Civil Society Partners for COVID-19 Solidarity.

Scientists evaluating the first known reinfection in the United States explain, “What is worrisome is that SARS-CoV-2 reinfection resulted in worse disease than did the first infection, requiring oxygen support and hospitalisation. The patient had positive antibodies after the reinfection, but whether he had pre-existing antibody after the first infection is unknown.”


by Micheal John


 

Hence, COVID-19 will be a comorbid illness to itself upon reinfection and the course outcome will be worse in future occurrence leading either to death or critical cell damage to organs and vulnerability to a third infection.

What does the cyclic component of the pandemic mean?

“It means that if SARS2 doesn’t kill a patient on the first infection it will accomplish that on the third, fourth or future reinfection as the years go by,” explains Harris.

Wear your N95 mask, maintain social distancing and wash hands frequently.

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the strain of coronavirus that causes COVID-19 respiratory-initiated illness causing the current COVID-19 pandemic.

COVID-19 reinfections of patients with underlying consequences of initial infection as comorbid vulnerabilities

COVID-19 reinfections of patients with underlying consequences of initial infection as comorbid vulnerabilities. Art/Cropping/Enhancement: Rosa Yamamoto FPMag
Photo credit: Micheal John / FPMag

The picture and its story: Study of antibodies for coronaviruses indicate antibodies may be very short-lived.  (cite: Seasonal coronavirus protective immunity is short-lasting. Nat Med. 2020; published online Sept 14.)

This is as true of the SARS-CoV-2 virus as it was for SARS1. COVID-19 patients around the world are now in the incipient stages of reinfection as the patient anti-bodies deplete. (cite: Genomic evidence for reinfection with SARS-CoV-2: a case study.
Lancet Infect Dis. 2020; published online Oct 12.)

This could mean COVID-19 will cycle through the human population creating comorbid underlying vulnerabilities of its own previous infection & raise the IFR. (cite: Duration of infectiousness and correlation with RT-PCR cycle threshold values in cases of COVID-19, England, January to May 2020.)

This cyclic infection pattern’s end game is species extermination unless stopped.

Stopping COVID-19  may require a long-lasting vaccine that bolsters T-Cells.

Reinfection of COVID-19 has begun as antibodies wear deplete

Reinfection of COVID-19 has begun as antibodies deplete. Photo Credit: Melissa Hemingway / FPMag Art/Cropping/Enhancement: Rosa Yamamoto FPMag

Background reading: 

  1. Wear an N-95 mask. SARS-CoV-2 is in the air.
  2. Ignore the fool. Wear an N95 respirator. Nothing else is working.

“Introductory lectures for training RINJ Nurses have included a warning of the reinfections of SARS-COV-2 becoming comorbid to the consequences of the first infections,” explains Monique Deslauriers, director of the USA RINJ organization.

“This is one of the reasons medical workers must be protected from becoming SARS2-infected. There is not enough time to train and certify new doctors and nurses for the course of the pandemic, besides the moral implications of allowing medical workers to become overwhelmed and die as a result of reckless individuals not wearing masks, keeping themselves clean and maintaining social distancing,” explained Dr. Anderson of eh RINJ Foundation.

“This is what I have been listening to repeatedly during the CEO lecture to first-start nurses on the importance of PPE while off-duty and on-duty. This comes from the Board of Directors medical advisors of the RINJ Foundation and it is a stark warning,” she adds.

“It is a pathogenic single-stranded RNA virus (+ssRNA) and it kills patients at an infection fatality rate some four to ten times greater than influenza. That varies by a community’s typical vulnerabilities (for example, in the USA the prevalent comorbidity is obesity) may increase as re-infections become more common in 2021 and the year after.

SARS2 may re-infect everyone and continue to kill a growing percentage of victims as it re-infects patients having CoV-damaged organs.

 


Take a self-training video course on wearing a mask.


 

As antibodies-wear down, re-infection creates a new Comorbid underlying Illness. COVID-19 itself.

“It could be a growing percentage of fatalities because conceivably, as SARS2 re-infects a patient, it is storming pulmonary and other cells within an immune system that is damaged from the first, second or third infection.

“The urgent fact remains that whatever it takes, this SARS2 virus must be stopped by any means. If it continues re-infecting the surviving patients and kills .6-.9%-?%-?% — survivors will become weaker and humans fewer with every wave of the virus, until we are all gone?

“There are many things we don’t know. But in what we are saying today you will learn what we must be preparing for and know that the fight is on. We must beat this virus.”

 

Known Reinfections present Worrisome Outcomes

“Richard L Tillett and colleagues describe the first confirmed case of SARS-CoV-2 reinfection in the USA.2 A 25-year-old man from the US state of Nevada, who had no known immune disorders, had PCR-confirmed SARS-CoV-2 infection in April, 2020 (cycle threshold [Ct] value 35·24; specimen A). He recovered in quarantine, testing negative by RT-PCR at two consecutive time points thereafter. However, 48 days after the initial test, the patient tested positive again by RT-PCR (Ct value 35·31; specimen B). Viral genome sequencing showed that both specimens A and B belonged to clade 20C, a predominant clade seen in northern Nevada. However, the genome sequences of isolates from the first infection (specimen A) and reinfection (specimen B) differed significantly, making the chance of the virus being from the same infection small. What is worrisome is that SARS-CoV-2 reinfection resulted in worse disease than did the first infection, requiring oxygen support and hospitalisation. The patient had positive antibodies after the reinfection, but whether he had pre-existing antibody after the first infection is unknown.”

Characteristics associated with reinfection with SARS-CoV-2

Location Gender Age 1st infected  (ct) 2nd (ct) Days Between Antibody after 2nd
Hong Kong Male 33 Mild (N/A) Asymptomatic (27) 142 IgG+
Nevada, USA Male 25 Mild (35) Hospitalised (35) 48 IgM+ and IgG+
Belgium Female 51 Mild (26–27) Milder (33) 93 IgG+
Ecuador Male 46 Mild (37) Worse (N/A) 63 IgM+ and IgG+
Source: Lancet. Data were obtained Sept 14, 2020, for reinfection cases confirmed by
viral genome sequences. Ct=cycle threshold. N/A=not available.
SARS-CoV-2=severe acute respiratory syndrome coronavirus 2.

Reinfections of COVID-19 are now being tracked around the world. This indicates a cyclical community spread of COVID-19 as warned of in previous articles by the biostatisticians on the Civil Society COVID-19 Solidarity Team.

 


Take a self-training video course on wearing a mask.


 

Some lessons on Mask wearing. Photo credit: Micheal John/FPMag One of many types of medical masks.

The picture and its story:

COVID-19 is a respiratory system initiated illness hence people must protect their respiratory system.

Wear a NIOSH N95 mask outside your home & near anyone in your home who has symptoms or who is quarantined.

This is true for all humans without exception. Learn to fit check & wear these masks below. Take the video course. It’s your future.

If an N95 mask is not available, wear a mask made of three layers of unique-weave cloth material.


Take a self-training video course on wearing a mask.


Three masks are needed for each person.

To clean your mask during 48-to-72-hour non-wearing intervals, leave it in a sunny place to dry. Do not try any other methods unless you are a pro and really know what you are doing.


254 Locales report 552,457,788 COVID-19 cases of which there are 17,000,202 active cases, therefore 529,079,599 recoveries and 6,377,987 fatalities.

GMT 2022-07-01 15:23

Data reported should be in accordance with the applied case definitions and testing strategies in each locale as their governments report daily or from time to time. All data researched and published by The RINJ Foundation and partners in CSPaC.

©The RINJ Foundation 2020-2022-07-01T15:23:28Z #Singapore-SK-HUK-77
RINJ is with Civil Society Solidarity Partners against COVID-19.

SARS2 Update 2022-07-01 15:23 GMT

  • Global Population: 7,903,501,966
  • 254 Regions reported 552,457,788 cases
  • 17,000,202 cases active
  • 6,377,987 people reported killed by COVID-19
  • 1.15% is current Case Fatality Rate (CFR)
  • 529,079,599 survived COVID-19
Beta Technology Global Estimates
  • 38.65% of all humans (3,055,091,567) have been infected
  • 0.63% Global estimated inferred average Infection Fatality Rate (IFR)
    (influenza is .1% or 6 per 100k (2019))
  • 19,127,264 Total deaths (CSPaC.net estimated actual) including errors, unexpected deaths with pneumonia indications with no history, and unreported likely-cause excess deaths such as people who never went to a hospital but had COVID-19 indications but never tested.

See The Lancet estimate of excess mortality from COVID-19 (Download PDF) in 191 countries/territories and 252 subnational units of select countries, from 1 January 2 0 2 0, to 31 December 2 0 2 1.

USA (88,950,302)
  • 145.94% of the USA may have been infected including reported + estimated unreported mild and estimated asymptomatic (485,703,726.76) persons, some of whom may not have been ill in their first course of the disease, but could have spread the disease.
  • 1.18% is USA current Case Fatality Rate (CFR) &
  • 0.27% is estimated inferred average Infection Fatality Rate (IFR)
  • 1,311,400 estimated total COVID-19 deaths including unreported likely-cause excess deaths. According to projections of IHME, IHME calculation of excess deaths is slightly higher than what CSPaC is showing.
  • See The Lancet estimate of excess mortality from COVID-19 (Download PDF) in 191 countries/territories and 252 subnational units of select countries, from 1 January 2 0 2 0, to 31 December 2 0 2 1.

    The American Epicenter has 17.60 % of global 'active' cases (2,991,233 USA / 17,000,202 Global), people infected with COVID-19 now.

Below: CSPAC estimated 2022-07-01 15:18 GMT COVID-19 data for India.

EPICENTER-2: India (43,471,282)

Reported*Cases*Deaths*CFR*Recovered
India43,471,282525,1391.2%42,836,906
*Reported by India but understated.

Note: India's reported death sum and cured data are widely seen among epidemiologists and biostatisticians as unreliable. For example, 3,045,754 is CSPAC estimated sum of deaths while India reports 525,139, creating the largest discepency in the world. India might only report hospital tested cases. Sources among hundreds of nurses and other medical practitioners provide a picture that in summary concludes most cases never present in a hospital especially in northern provinces where health care is less available and utilization is low anyway because of poverty, hence most people die at home in India. This theory could explain discrepancies between reported data and algorithmic estimates.

LocaleCasesDeathsActive
India reported:43,471,282525,139109,237
India estimates:240,396,1893,045,754462,344

Data collected and reported by: Civil Society Solidarity Partners against COVID-19